منابع مشابه
Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug.
A high dose of delta9-tetrahydrocannabinol, the main Cannabis sativa (cannabis) component, induces anxiety and psychotic-like symptoms in healthy volunteers. These effects of delta9-tetrahydrocannabinol are significantly reduced by cannabidiol (CBD), a cannabis constituent which is devoid of the typical effects of the plant. This observation led us to suspect that CBD could have anxiolytic and/...
متن کاملCannabidiol as potential anticancer drug.
Over the past years, several lines of evidence support an antitumourigenic effect of cannabinoids including Δ(9)-tetrahydrocannabinol (Δ(9)-THC), synthetic agonists, endocannabinoids and endocannabinoid transport or degradation inhibitors. Indeed, cannabinoids possess anti-proliferative and pro-apoptotic effects and they are known to interfere with tumour neovascularization, cancer cell migrati...
متن کاملCannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.
OBJECTIVES To review and describe studies of the non-psychotomimetic constituent of Cannabis sativa, cannabidiol (CBD), as an anxiolytic drug and discuss its possible mechanisms of action. METHOD The articles selected for the review were identified through searches in English, Portuguese, and Spanish in the electronic databases ISI Web of Knowledge, SciELO, PubMed, and PsycINFO, combining the...
متن کاملCannabidiol as a Potential New Type of an Antipsychotic. A Critical Review of the Evidence
There is urgent need for the development of mechanistically different and less side-effect prone antipsychotic compounds. The endocannabinoid system has been suggested to represent a potential new target in this indication. While the chronic use of cannabis itself has been considered a risk factor contributing to the development of schizophrenia, triggered by the phytocannabinoid delta-9-tetrah...
متن کاملAntipsychotic drug overdose.
EMERGENCY nurse 17 Antipsychotic drugs (or neuroleptics) are a large class of drugs which can be divided into three groups: phenothiazine, miscellaneous and atypical (Box 1). They are used to tranquillise patients without impairing consciousness and without causing paradoxical excitement. They are often referred to as major tranquillisers but this is misleading since these drugs also relieve fl...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2018
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sby014.050